Scientific Advances in Lung Cancer 2015.
Identifieur interne : 001762 ( Main/Exploration ); précédent : 001761; suivant : 001763Scientific Advances in Lung Cancer 2015.
Auteurs : Anne S. Tsao [États-Unis] ; Giorgio V. Scagliotti [Italie] ; Paul A. Bunn [États-Unis] ; David P. Carbone [États-Unis] ; Graham W. Warren [États-Unis] ; Chunxue Bai [République populaire de Chine] ; Harry J. De Koning [Pays-Bas] ; A Uraujh Yousaf-Khan [Pays-Bas] ; Annette Mcwilliams [Australie] ; Ming Sound Tsao [Canada] ; Prasad S. Adusumilli [États-Unis] ; Ram N Rami-Porta [Espagne] ; Hisao Asamura [Japon] ; Paul E. Van Schil [Belgique] ; Gail E. Darling [Canada] ; Suresh S. Ramalingam [Géorgie (pays)] ; Daniel R. Gomez [États-Unis] ; Kenneth E. Rosenzweig [États-Unis] ; Stefan Zimmermann [Suisse] ; Solange Peters [Suisse] ; Sai-Hong Ignatius Ou [États-Unis] ; Thanyanan Reungwetwattana [Thaïlande] ; Pasi A. J Nne [États-Unis] ; Tony S. Mok [République populaire de Chine] ; Heather A. Wakelee [États-Unis] ; Robert Pirker [Autriche] ; Julien Mazières [France] ; Julie R. Brahmer [États-Unis] ; Yang Zhou [États-Unis] ; Roy S. Herbst [États-Unis] ; Vassiliki A. Papadimitrakopoulou [États-Unis] ; Mary W. Redman [États-Unis] ; Murry W. Wynes [États-Unis] ; David R. Gandara [États-Unis] ; Ronan J. Kelly [États-Unis] ; Fred R. Hirsch [États-Unis] ; Harvey I. Pass [États-Unis]Source :
- Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [ 1556-1380 ] ; 2016.
Abstract
Lung cancer continues to be a major global health problem; the disease is diagnosed in more than 1.6 million new patients each year. However, significant progress is underway in both the prevention and treatment of lung cancer. Lung cancer therapy has now emerged as a "role model" for precision cancer medicine, with several important therapeutic breakthroughs occurring during 2015. These advances have occurred primarily in the immunotherapy field and in treatments directed against tumors harboring specific oncogenic drivers. Our knowledge about molecular mechanisms for oncogene-driven tumors and about resistance to targeted therapies has increased quickly over the past year. As a result, several regulatory approvals of new agents that significantly improve survival and quality of life for patients with lung cancer who have advanced disease have occurred. The International Association for the Study of Lung Cancer has gathered experts in different areas of lung cancer research and management to summarize the most significant scientific advancements related to prevention and therapy of lung cancer during the past year.
DOI: 10.1016/j.jtho.2016.03.012
PubMed: 27013409
Affiliations:
- Australie, Autriche, Belgique, Canada, Espagne, France, Géorgie (pays), Italie, Japon, Pays-Bas, République populaire de Chine, Suisse, Thaïlande, États-Unis
- Californie, Canton de Vaud, Caroline du Sud, Catalogne, Colorado, Connecticut, Hollande-Méridionale, Maryland, Massachusetts, Midi-Pyrénées, Occitanie (région administrative), Ohio, Ontario, Région de Kantō, Texas, Vienne (Autriche), Washington (État), État de New York
- Barcelone, Lausanne, Rotterdam, Sha Tin, Tokyo, Toronto, Toulouse, Vienne (Autriche)
- Université chinoise de Hong Kong, Université de Toronto
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Anderson Cancer Center, Houston</wicri:cityArea></affiliation></author><author><name sortKey="Rosenzweig, Kenneth E" sort="Rosenzweig, Kenneth E" uniqKey="Rosenzweig K" first="Kenneth E" last="Rosenzweig">Kenneth E. Rosenzweig</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology at Icahn School of Medicine at Mount Sinai, New York, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Radiation Oncology at Icahn School of Medicine at Mount Sinai, New York</wicri:cityArea></affiliation></author><author><name sortKey="Zimmermann, Stefan" sort="Zimmermann, Stefan" uniqKey="Zimmermann S" first="Stefan" last="Zimmermann">Stefan Zimmermann</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, HFR Fribourg, Fribourg, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Oncology, HFR Fribourg, Fribourg</wicri:regionArea><wicri:noRegion>Fribourg</wicri:noRegion></affiliation></author><author><name sortKey="Peters, Solange" sort="Peters, Solange" uniqKey="Peters S" first="Solange" last="Peters">Solange Peters</name><affiliation wicri:level="3"><nlm:affiliation>Department of Oncology, University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Oncology, University of Lausanne, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Ignatius Ou, Sai Hong" sort="Ignatius Ou, Sai Hong" uniqKey="Ignatius Ou S" first="Sai-Hong" last="Ignatius Ou">Sai-Hong Ignatius Ou</name><affiliation wicri:level="2"><nlm:affiliation>Chao Family Comprehensive Cancer Center, Division of Hematology-Oncology, Department of Medicine, University of California Irvine School of Medicine, Orange, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Chao Family Comprehensive Cancer Center, Division of Hematology-Oncology, Department of Medicine, University of California Irvine School of Medicine, Orange</wicri:cityArea></affiliation></author><author><name sortKey="Reungwetwattana, Thanyanan" sort="Reungwetwattana, Thanyanan" uniqKey="Reungwetwattana T" first="Thanyanan" last="Reungwetwattana">Thanyanan Reungwetwattana</name><affiliation wicri:level="1"><nlm:affiliation>Division of Medical Oncology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Division of Medical Oncology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="J Nne, Pasi A" sort="J Nne, Pasi A" uniqKey="J Nne P" first="Pasi A" last="J Nne">Pasi A. J Nne</name><affiliation wicri:level="2"><nlm:affiliation>Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dana Farber Cancer Institute, Harvard Medical School, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Mok, Tony S" sort="Mok, Tony S" uniqKey="Mok T" first="Tony S" last="Mok">Tony S. Mok</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Oncology, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People's Republic of China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Clinical Oncology, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Wakelee, Heather A" sort="Wakelee, Heather A" uniqKey="Wakelee H" first="Heather A" last="Wakelee">Heather A. Wakelee</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford</wicri:cityArea></affiliation></author><author><name sortKey="Pirker, Robert" sort="Pirker, Robert" uniqKey="Pirker R" first="Robert" last="Pirker">Robert Pirker</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medicine I, Medical University of Vienna, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Medicine I, Medical University of Vienna, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Mazieres, Julien" sort="Mazieres, Julien" uniqKey="Mazieres J" first="Julien" last="Mazières">Julien Mazières</name><affiliation wicri:level="3"><nlm:affiliation>Larrey Hospital, Paul Sabatier University, Toulouse, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Larrey Hospital, Paul Sabatier University, Toulouse</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Brahmer, Julie R" sort="Brahmer, Julie R" uniqKey="Brahmer J" first="Julie R" last="Brahmer">Julie R. Brahmer</name><affiliation wicri:level="2"><nlm:affiliation>Johns Hopkins Kimmel Cancer Center, Johns Hopkins, Baltimore, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Johns Hopkins Kimmel Cancer Center, Johns Hopkins, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Zhou, Yang" sort="Zhou, Yang" uniqKey="Zhou Y" first="Yang" last="Zhou">Yang Zhou</name><affiliation wicri:level="2"><nlm:affiliation>Yale Comprehensive Cancer Center, Yale School of Medicine, New Haven, Connecticut.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale Comprehensive Cancer Center, Yale School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Herbst, Roy S" sort="Herbst, Roy S" uniqKey="Herbst R" first="Roy S" last="Herbst">Roy S. Herbst</name><affiliation wicri:level="2"><nlm:affiliation>Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven, New Haven, Connecticut.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Papadimitrakopoulou, Vassiliki A" sort="Papadimitrakopoulou, Vassiliki A" uniqKey="Papadimitrakopoulou V" first="Vassiliki A" last="Papadimitrakopoulou">Vassiliki A. Papadimitrakopoulou</name><affiliation wicri:level="2"><nlm:affiliation>Department of Thoracic/Head and Neck Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, Texas.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Department of Thoracic/Head and Neck Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston</wicri:cityArea></affiliation></author><author><name sortKey="Redman, Mary W" sort="Redman, Mary W" uniqKey="Redman M" first="Mary W" last="Redman">Mary W. Redman</name><affiliation wicri:level="2"><nlm:affiliation>Fred Hutchinson Cancer Research Center, Public Health Sciences Division Seattle, Washington.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Washington (État)</region></placeName><wicri:cityArea>Fred Hutchinson Cancer Research Center, Public Health Sciences Division Seattle</wicri:cityArea></affiliation></author><author><name sortKey="Wynes, Murry W" sort="Wynes, Murry W" uniqKey="Wynes M" first="Murry W" last="Wynes">Murry W. 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Gandara</name><affiliation wicri:level="2"><nlm:affiliation>Thoracic Oncology Program, UC Davis Comprehensive Cancer Center, Sacramento, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Thoracic Oncology Program, UC Davis Comprehensive Cancer Center, Sacramento</wicri:cityArea></affiliation></author><author><name sortKey="Kelly, Ronan J" sort="Kelly, Ronan J" uniqKey="Kelly R" first="Ronan J" last="Kelly">Ronan J. Kelly</name><affiliation wicri:level="2"><nlm:affiliation>Sidney Kimmel Comprehensive Cancer Center Johns Hopkins, Johns Hopkins, Baltimore, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Sidney Kimmel Comprehensive Cancer Center Johns Hopkins, Johns Hopkins, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Hirsch, Fred R" sort="Hirsch, Fred R" uniqKey="Hirsch F" first="Fred R" last="Hirsch">Fred R. Hirsch</name><affiliation wicri:level="2"><nlm:affiliation>Division of Medical Oncology, University of Colorado Cancer Center, Aurora, Colorado. Electronic address: Fred.Hirsch@ucdenver.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Colorado</region></placeName><wicri:cityArea>Division of Medical Oncology, University of Colorado Cancer Center, Aurora</wicri:cityArea></affiliation></author><author><name sortKey="Pass, Harvey I" sort="Pass, Harvey I" uniqKey="Pass H" first="Harvey I" last="Pass">Harvey I. Pass</name><affiliation wicri:level="2"><nlm:affiliation>Department of Cardiothoracic Surgery, New York University Langone Medical Center, New York, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Cardiothoracic Surgery, New York University Langone Medical Center, New York</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27013409</idno><idno type="pmid">27013409</idno><idno type="doi">10.1016/j.jtho.2016.03.012</idno><idno type="wicri:Area/PubMed/Corpus">001F37</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001F37</idno><idno type="wicri:Area/PubMed/Curation">001F13</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001F13</idno><idno type="wicri:Area/PubMed/Checkpoint">001F13</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001F13</idno><idno type="wicri:Area/Ncbi/Merge">003330</idno><idno type="wicri:Area/Ncbi/Curation">003330</idno><idno type="wicri:Area/Ncbi/Checkpoint">003330</idno><idno type="wicri:Area/Main/Merge">001757</idno><idno type="wicri:Area/Main/Curation">001762</idno><idno type="wicri:Area/Main/Exploration">001762</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Scientific Advances in Lung Cancer 2015.</title><author><name sortKey="Tsao, Anne S" sort="Tsao, Anne S" uniqKey="Tsao A" first="Anne S" last="Tsao">Anne S. Tsao</name><affiliation wicri:level="2"><nlm:affiliation>Department of Thoracic/Head and Neck Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, Texas.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Department of Thoracic/Head and Neck Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston</wicri:cityArea></affiliation></author><author><name sortKey="Scagliotti, Giorgio V" sort="Scagliotti, Giorgio V" uniqKey="Scagliotti G" first="Giorgio V" last="Scagliotti">Giorgio V. Scagliotti</name><affiliation wicri:level="1"><nlm:affiliation>San Luigi Hospital, University of Turin, Orbassano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>San Luigi Hospital, University of Turin, Orbassano</wicri:regionArea><wicri:noRegion>Orbassano</wicri:noRegion></affiliation></author><author><name sortKey="Bunn, Paul A" sort="Bunn, Paul A" uniqKey="Bunn P" first="Paul A" last="Bunn">Paul A. Bunn</name><affiliation wicri:level="2"><nlm:affiliation>Division of Medical Oncology, University of Colorado Cancer Center, Aurora, Colorado.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Colorado</region></placeName><wicri:cityArea>Division of Medical Oncology, University of Colorado Cancer Center, Aurora</wicri:cityArea></affiliation></author><author><name sortKey="Carbone, David P" sort="Carbone, David P" uniqKey="Carbone D" first="David P" last="Carbone">David P. Carbone</name><affiliation wicri:level="2"><nlm:affiliation>Division of Medical Oncology, The Ohio State University, Columbus, Ohio.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Division of Medical Oncology, The Ohio State University, Columbus</wicri:cityArea></affiliation></author><author><name sortKey="Warren, Graham W" sort="Warren, Graham W" uniqKey="Warren G" first="Graham W" last="Warren">Graham W. Warren</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, South Carolina.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName><wicri:cityArea>Department of Radiation Oncology, Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston</wicri:cityArea></affiliation></author><author><name sortKey="Bai, Chunxue" sort="Bai, Chunxue" uniqKey="Bai C" first="Chunxue" last="Bai">Chunxue Bai</name><affiliation wicri:level="1"><nlm:affiliation>Shanghai Respiratory Research Institute, Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, People's Republic of China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Shanghai Respiratory Research Institute, Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University</wicri:regionArea><wicri:noRegion>Fudan University</wicri:noRegion></affiliation></author><author><name sortKey="De Koning, Harry J" sort="De Koning, Harry J" uniqKey="De Koning H" first="Harry J" last="De Koning">Harry J. De Koning</name><affiliation wicri:level="3"><nlm:affiliation>Erasmus Medical Center, University Medical Center Rotterdam, Department of Public Health, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Erasmus Medical Center, University Medical Center Rotterdam, Department of Public Health, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Yousaf Khan, A Uraujh" sort="Yousaf Khan, A Uraujh" uniqKey="Yousaf Khan A" first="A Uraujh" last="Yousaf-Khan">A Uraujh Yousaf-Khan</name><affiliation wicri:level="3"><nlm:affiliation>Erasmus Medical Center, University Medical Center Rotterdam, Department of Public Health, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Erasmus Medical Center, University Medical Center Rotterdam, Department of Public Health, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Mcwilliams, Annette" sort="Mcwilliams, Annette" uniqKey="Mcwilliams A" first="Annette" last="Mcwilliams">Annette Mcwilliams</name><affiliation wicri:level="1"><nlm:affiliation>Fiona Stanley Hospital, Murdoch, Western Australia and University of Western Australia, Perth, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Fiona Stanley Hospital, Murdoch, Western Australia and University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Tsao, Ming Sound" sort="Tsao, Ming Sound" uniqKey="Tsao M" first="Ming Sound" last="Tsao">Ming Sound Tsao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Laboratory Medicine and Pathobiology, University Health Network and Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Laboratory Medicine and Pathobiology, University Health Network and Princess Margaret Cancer Centre, University of Toronto, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Adusumilli, Prasad S" sort="Adusumilli, Prasad S" uniqKey="Adusumilli P" first="Prasad S" last="Adusumilli">Prasad S. Adusumilli</name><affiliation wicri:level="2"><nlm:affiliation>Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York; Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York; Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York</wicri:cityArea></affiliation></author><author><name sortKey="Rami Porta, Ram N" sort="Rami Porta, Ram N" uniqKey="Rami Porta R" first="Ram N" last="Rami-Porta">Ram N Rami-Porta</name><affiliation wicri:level="3"><nlm:affiliation>Department of Thoracic Surgery, Hospital Universitari Mutua Terrassa, University of Barcelona, Barcelona, Spain; Centros de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES) Lung Cancer Group, Terrassa, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Thoracic Surgery, Hospital Universitari Mutua Terrassa, University of Barcelona, Barcelona, Spain; Centros de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES) Lung Cancer Group, Terrassa, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Asamura, Hisao" sort="Asamura, Hisao" uniqKey="Asamura H" first="Hisao" last="Asamura">Hisao Asamura</name><affiliation wicri:level="3"><nlm:affiliation>Division of Thoracic Surgery, Keio University School of Medicine, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Thoracic Surgery, Keio University School of Medicine, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Van Schil, Paul E" sort="Van Schil, Paul E" uniqKey="Van Schil P" first="Paul E" last="Van Schil">Paul E. Van Schil</name><affiliation wicri:level="1"><nlm:affiliation>Department of Thoracic and Vascular Surgery, Antwerp University Hospital, Edegem (Antwerp), Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Thoracic and Vascular Surgery, Antwerp University Hospital, Edegem (Antwerp)</wicri:regionArea><wicri:noRegion>Edegem (Antwerp)</wicri:noRegion></affiliation></author><author><name sortKey="Darling, Gail E" sort="Darling, Gail E" uniqKey="Darling G" first="Gail E" last="Darling">Gail E. Darling</name><affiliation wicri:level="4"><nlm:affiliation>Division of Thoracic Surgery University of Toronto, Toronto, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Thoracic Surgery University of Toronto, Toronto</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Ramalingam, Suresh S" sort="Ramalingam, Suresh S" uniqKey="Ramalingam S" first="Suresh S" last="Ramalingam">Suresh S. Ramalingam</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hematology & Medical Oncology, Emory University School of Medicine, Atlanta, Georgia.</nlm:affiliation><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Department of Hematology & Medical Oncology, Emory University School of Medicine, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Gomez, Daniel R" sort="Gomez, Daniel R" uniqKey="Gomez D" first="Daniel R" last="Gomez">Daniel R. Gomez</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston</wicri:cityArea></affiliation></author><author><name sortKey="Rosenzweig, Kenneth E" sort="Rosenzweig, Kenneth E" uniqKey="Rosenzweig K" first="Kenneth E" last="Rosenzweig">Kenneth E. Rosenzweig</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology at Icahn School of Medicine at Mount Sinai, New York, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Radiation Oncology at Icahn School of Medicine at Mount Sinai, New York</wicri:cityArea></affiliation></author><author><name sortKey="Zimmermann, Stefan" sort="Zimmermann, Stefan" uniqKey="Zimmermann S" first="Stefan" last="Zimmermann">Stefan Zimmermann</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, HFR Fribourg, Fribourg, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Oncology, HFR Fribourg, Fribourg</wicri:regionArea><wicri:noRegion>Fribourg</wicri:noRegion></affiliation></author><author><name sortKey="Peters, Solange" sort="Peters, Solange" uniqKey="Peters S" first="Solange" last="Peters">Solange Peters</name><affiliation wicri:level="3"><nlm:affiliation>Department of Oncology, University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Oncology, University of Lausanne, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Ignatius Ou, Sai Hong" sort="Ignatius Ou, Sai Hong" uniqKey="Ignatius Ou S" first="Sai-Hong" last="Ignatius Ou">Sai-Hong Ignatius Ou</name><affiliation wicri:level="2"><nlm:affiliation>Chao Family Comprehensive Cancer Center, Division of Hematology-Oncology, Department of Medicine, University of California Irvine School of Medicine, Orange, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Chao Family Comprehensive Cancer Center, Division of Hematology-Oncology, Department of Medicine, University of California Irvine School of Medicine, Orange</wicri:cityArea></affiliation></author><author><name sortKey="Reungwetwattana, Thanyanan" sort="Reungwetwattana, Thanyanan" uniqKey="Reungwetwattana T" first="Thanyanan" last="Reungwetwattana">Thanyanan Reungwetwattana</name><affiliation wicri:level="1"><nlm:affiliation>Division of Medical Oncology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Division of Medical Oncology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="J Nne, Pasi A" sort="J Nne, Pasi A" uniqKey="J Nne P" first="Pasi A" last="J Nne">Pasi A. J Nne</name><affiliation wicri:level="2"><nlm:affiliation>Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dana Farber Cancer Institute, Harvard Medical School, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Mok, Tony S" sort="Mok, Tony S" uniqKey="Mok T" first="Tony S" last="Mok">Tony S. Mok</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Oncology, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People's Republic of China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Clinical Oncology, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Wakelee, Heather A" sort="Wakelee, Heather A" uniqKey="Wakelee H" first="Heather A" last="Wakelee">Heather A. Wakelee</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford</wicri:cityArea></affiliation></author><author><name sortKey="Pirker, Robert" sort="Pirker, Robert" uniqKey="Pirker R" first="Robert" last="Pirker">Robert Pirker</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medicine I, Medical University of Vienna, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Medicine I, Medical University of Vienna, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Mazieres, Julien" sort="Mazieres, Julien" uniqKey="Mazieres J" first="Julien" last="Mazières">Julien Mazières</name><affiliation wicri:level="3"><nlm:affiliation>Larrey Hospital, Paul Sabatier University, Toulouse, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Larrey Hospital, Paul Sabatier University, Toulouse</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Brahmer, Julie R" sort="Brahmer, Julie R" uniqKey="Brahmer J" first="Julie R" last="Brahmer">Julie R. Brahmer</name><affiliation wicri:level="2"><nlm:affiliation>Johns Hopkins Kimmel Cancer Center, Johns Hopkins, Baltimore, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Johns Hopkins Kimmel Cancer Center, Johns Hopkins, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Zhou, Yang" sort="Zhou, Yang" uniqKey="Zhou Y" first="Yang" last="Zhou">Yang Zhou</name><affiliation wicri:level="2"><nlm:affiliation>Yale Comprehensive Cancer Center, Yale School of Medicine, New Haven, Connecticut.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale Comprehensive Cancer Center, Yale School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Herbst, Roy S" sort="Herbst, Roy S" uniqKey="Herbst R" first="Roy S" last="Herbst">Roy S. Herbst</name><affiliation wicri:level="2"><nlm:affiliation>Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven, New Haven, Connecticut.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Papadimitrakopoulou, Vassiliki A" sort="Papadimitrakopoulou, Vassiliki A" uniqKey="Papadimitrakopoulou V" first="Vassiliki A" last="Papadimitrakopoulou">Vassiliki A. Papadimitrakopoulou</name><affiliation wicri:level="2"><nlm:affiliation>Department of Thoracic/Head and Neck Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, Texas.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Department of Thoracic/Head and Neck Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston</wicri:cityArea></affiliation></author><author><name sortKey="Redman, Mary W" sort="Redman, Mary W" uniqKey="Redman M" first="Mary W" last="Redman">Mary W. Redman</name><affiliation wicri:level="2"><nlm:affiliation>Fred Hutchinson Cancer Research Center, Public Health Sciences Division Seattle, Washington.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Washington (État)</region></placeName><wicri:cityArea>Fred Hutchinson Cancer Research Center, Public Health Sciences Division Seattle</wicri:cityArea></affiliation></author><author><name sortKey="Wynes, Murry W" sort="Wynes, Murry W" uniqKey="Wynes M" first="Murry W" last="Wynes">Murry W. Wynes</name><affiliation wicri:level="2"><nlm:affiliation>International Association for the Study of Lung Cancer, Aurora, Colorado.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Colorado</region></placeName><wicri:cityArea>International Association for the Study of Lung Cancer, Aurora</wicri:cityArea></affiliation></author><author><name sortKey="Gandara, David R" sort="Gandara, David R" uniqKey="Gandara D" first="David R" last="Gandara">David R. Gandara</name><affiliation wicri:level="2"><nlm:affiliation>Thoracic Oncology Program, UC Davis Comprehensive Cancer Center, Sacramento, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Thoracic Oncology Program, UC Davis Comprehensive Cancer Center, Sacramento</wicri:cityArea></affiliation></author><author><name sortKey="Kelly, Ronan J" sort="Kelly, Ronan J" uniqKey="Kelly R" first="Ronan J" last="Kelly">Ronan J. Kelly</name><affiliation wicri:level="2"><nlm:affiliation>Sidney Kimmel Comprehensive Cancer Center Johns Hopkins, Johns Hopkins, Baltimore, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Sidney Kimmel Comprehensive Cancer Center Johns Hopkins, Johns Hopkins, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Hirsch, Fred R" sort="Hirsch, Fred R" uniqKey="Hirsch F" first="Fred R" last="Hirsch">Fred R. Hirsch</name><affiliation wicri:level="2"><nlm:affiliation>Division of Medical Oncology, University of Colorado Cancer Center, Aurora, Colorado. Electronic address: Fred.Hirsch@ucdenver.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Colorado</region></placeName><wicri:cityArea>Division of Medical Oncology, University of Colorado Cancer Center, Aurora</wicri:cityArea></affiliation></author><author><name sortKey="Pass, Harvey I" sort="Pass, Harvey I" uniqKey="Pass H" first="Harvey I" last="Pass">Harvey I. Pass</name><affiliation wicri:level="2"><nlm:affiliation>Department of Cardiothoracic Surgery, New York University Langone Medical Center, New York, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Cardiothoracic Surgery, New York University Langone Medical Center, New York</wicri:cityArea></affiliation></author></analytic><series><title level="j">Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer</title><idno type="eISSN">1556-1380</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Lung cancer continues to be a major global health problem; the disease is diagnosed in more than 1.6 million new patients each year. However, significant progress is underway in both the prevention and treatment of lung cancer. Lung cancer therapy has now emerged as a "role model" for precision cancer medicine, with several important therapeutic breakthroughs occurring during 2015. These advances have occurred primarily in the immunotherapy field and in treatments directed against tumors harboring specific oncogenic drivers. Our knowledge about molecular mechanisms for oncogene-driven tumors and about resistance to targeted therapies has increased quickly over the past year. As a result, several regulatory approvals of new agents that significantly improve survival and quality of life for patients with lung cancer who have advanced disease have occurred. The International Association for the Study of Lung Cancer has gathered experts in different areas of lung cancer research and management to summarize the most significant scientific advancements related to prevention and therapy of lung cancer during the past year.</div></front></TEI><affiliations><list><country><li>Australie</li><li>Autriche</li><li>Belgique</li><li>Canada</li><li>Espagne</li><li>France</li><li>Géorgie (pays)</li><li>Italie</li><li>Japon</li><li>Pays-Bas</li><li>République populaire de Chine</li><li>Suisse</li><li>Thaïlande</li><li>États-Unis</li></country><region><li>Californie</li><li>Canton de Vaud</li><li>Caroline du Sud</li><li>Catalogne</li><li>Colorado</li><li>Connecticut</li><li>Hollande-Méridionale</li><li>Maryland</li><li>Massachusetts</li><li>Midi-Pyrénées</li><li>Occitanie (région administrative)</li><li>Ohio</li><li>Ontario</li><li>Région de Kantō</li><li>Texas</li><li>Vienne (Autriche)</li><li>Washington (État)</li><li>État de New York</li></region><settlement><li>Barcelone</li><li>Lausanne</li><li>Rotterdam</li><li>Sha Tin</li><li>Tokyo</li><li>Toronto</li><li>Toulouse</li><li>Vienne (Autriche)</li></settlement><orgName><li>Université chinoise de Hong Kong</li><li>Université de Toronto</li></orgName></list><tree><country name="États-Unis"><region name="Texas"><name sortKey="Tsao, Anne S" sort="Tsao, Anne S" uniqKey="Tsao A" first="Anne S" last="Tsao">Anne S. Tsao</name></region><name sortKey="Adusumilli, Prasad S" sort="Adusumilli, Prasad S" uniqKey="Adusumilli P" first="Prasad S" last="Adusumilli">Prasad S. Adusumilli</name><name sortKey="Brahmer, Julie R" sort="Brahmer, Julie R" uniqKey="Brahmer J" first="Julie R" last="Brahmer">Julie R. Brahmer</name><name sortKey="Bunn, Paul A" sort="Bunn, Paul A" uniqKey="Bunn P" first="Paul A" last="Bunn">Paul A. Bunn</name><name sortKey="Carbone, David P" sort="Carbone, David P" uniqKey="Carbone D" first="David P" last="Carbone">David P. Carbone</name><name sortKey="Gandara, David R" sort="Gandara, David R" uniqKey="Gandara D" first="David R" last="Gandara">David R. Gandara</name><name sortKey="Gomez, Daniel R" sort="Gomez, Daniel R" uniqKey="Gomez D" first="Daniel R" last="Gomez">Daniel R. Gomez</name><name sortKey="Herbst, Roy S" sort="Herbst, Roy S" uniqKey="Herbst R" first="Roy S" last="Herbst">Roy S. Herbst</name><name sortKey="Hirsch, Fred R" sort="Hirsch, Fred R" uniqKey="Hirsch F" first="Fred R" last="Hirsch">Fred R. Hirsch</name><name sortKey="Ignatius Ou, Sai Hong" sort="Ignatius Ou, Sai Hong" uniqKey="Ignatius Ou S" first="Sai-Hong" last="Ignatius Ou">Sai-Hong Ignatius Ou</name><name sortKey="J Nne, Pasi A" sort="J Nne, Pasi A" uniqKey="J Nne P" first="Pasi A" last="J Nne">Pasi A. J Nne</name><name sortKey="Kelly, Ronan J" sort="Kelly, Ronan J" uniqKey="Kelly R" first="Ronan J" last="Kelly">Ronan J. Kelly</name><name sortKey="Papadimitrakopoulou, Vassiliki A" sort="Papadimitrakopoulou, Vassiliki A" uniqKey="Papadimitrakopoulou V" first="Vassiliki A" last="Papadimitrakopoulou">Vassiliki A. Papadimitrakopoulou</name><name sortKey="Pass, Harvey I" sort="Pass, Harvey I" uniqKey="Pass H" first="Harvey I" last="Pass">Harvey I. Pass</name><name sortKey="Redman, Mary W" sort="Redman, Mary W" uniqKey="Redman M" first="Mary W" last="Redman">Mary W. Redman</name><name sortKey="Rosenzweig, Kenneth E" sort="Rosenzweig, Kenneth E" uniqKey="Rosenzweig K" first="Kenneth E" last="Rosenzweig">Kenneth E. Rosenzweig</name><name sortKey="Wakelee, Heather A" sort="Wakelee, Heather A" uniqKey="Wakelee H" first="Heather A" last="Wakelee">Heather A. Wakelee</name><name sortKey="Warren, Graham W" sort="Warren, Graham W" uniqKey="Warren G" first="Graham W" last="Warren">Graham W. Warren</name><name sortKey="Wynes, Murry W" sort="Wynes, Murry W" uniqKey="Wynes M" first="Murry W" last="Wynes">Murry W. Wynes</name><name sortKey="Zhou, Yang" sort="Zhou, Yang" uniqKey="Zhou Y" first="Yang" last="Zhou">Yang Zhou</name></country><country name="Italie"><noRegion><name sortKey="Scagliotti, Giorgio V" sort="Scagliotti, Giorgio V" uniqKey="Scagliotti G" first="Giorgio V" last="Scagliotti">Giorgio V. Scagliotti</name></noRegion></country><country name="République populaire de Chine"><noRegion><name sortKey="Bai, Chunxue" sort="Bai, Chunxue" uniqKey="Bai C" first="Chunxue" last="Bai">Chunxue Bai</name></noRegion><name sortKey="Mok, Tony S" sort="Mok, Tony S" uniqKey="Mok T" first="Tony S" last="Mok">Tony S. Mok</name></country><country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="De Koning, Harry J" sort="De Koning, Harry J" uniqKey="De Koning H" first="Harry J" last="De Koning">Harry J. De Koning</name></region><name sortKey="Yousaf Khan, A Uraujh" sort="Yousaf Khan, A Uraujh" uniqKey="Yousaf Khan A" first="A Uraujh" last="Yousaf-Khan">A Uraujh Yousaf-Khan</name></country><country name="Australie"><noRegion><name sortKey="Mcwilliams, Annette" sort="Mcwilliams, Annette" uniqKey="Mcwilliams A" first="Annette" last="Mcwilliams">Annette Mcwilliams</name></noRegion></country><country name="Canada"><noRegion><name sortKey="Tsao, Ming Sound" sort="Tsao, Ming Sound" uniqKey="Tsao M" first="Ming Sound" last="Tsao">Ming Sound Tsao</name></noRegion><name sortKey="Darling, Gail E" sort="Darling, Gail E" uniqKey="Darling G" first="Gail E" last="Darling">Gail E. Darling</name></country><country name="Espagne"><region name="Catalogne"><name sortKey="Rami Porta, Ram N" sort="Rami Porta, Ram N" uniqKey="Rami Porta R" first="Ram N" last="Rami-Porta">Ram N Rami-Porta</name></region></country><country name="Japon"><region name="Région de Kantō"><name sortKey="Asamura, Hisao" sort="Asamura, Hisao" uniqKey="Asamura H" first="Hisao" last="Asamura">Hisao Asamura</name></region></country><country name="Belgique"><noRegion><name sortKey="Van Schil, Paul E" sort="Van Schil, Paul E" uniqKey="Van Schil P" first="Paul E" last="Van Schil">Paul E. Van Schil</name></noRegion></country><country name="Géorgie (pays)"><noRegion><name sortKey="Ramalingam, Suresh S" sort="Ramalingam, Suresh S" uniqKey="Ramalingam S" first="Suresh S" last="Ramalingam">Suresh S. Ramalingam</name></noRegion></country><country name="Suisse"><noRegion><name sortKey="Zimmermann, Stefan" sort="Zimmermann, Stefan" uniqKey="Zimmermann S" first="Stefan" last="Zimmermann">Stefan Zimmermann</name></noRegion><name sortKey="Peters, Solange" sort="Peters, Solange" uniqKey="Peters S" first="Solange" last="Peters">Solange Peters</name></country><country name="Thaïlande"><noRegion><name sortKey="Reungwetwattana, Thanyanan" sort="Reungwetwattana, Thanyanan" uniqKey="Reungwetwattana T" first="Thanyanan" last="Reungwetwattana">Thanyanan Reungwetwattana</name></noRegion></country><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Pirker, Robert" sort="Pirker, Robert" uniqKey="Pirker R" first="Robert" last="Pirker">Robert Pirker</name></region></country><country name="France"><region name="Occitanie (région administrative)"><name sortKey="Mazieres, Julien" sort="Mazieres, Julien" uniqKey="Mazieres J" first="Julien" last="Mazières">Julien Mazières</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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